During a rave party organized on private property, two young girls are seen jumping off a cliff together. The autopsy reveals that they had been drugged to the bone : en explosive cocktails of ecstasy and ketamine. The police concludes suicide without a doubt.

In Paris, the body of a young Asian woman is found with her throat cut and vitriolized ; thirty tablets of ecstasy are hidden in her belt buckle. Nothing helps to establish her identity.

While commissioner Clémenti does not want to make a link between the two cases, Louise Morvan explodes the status quo by showing that suicide is absolutely not a factor in this story.